Status:
ACTIVE_NOT_RECRUITING
Comparing the Effects of Psilocin and Psilocybin in Healthy Adults
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
Filament Health Corp.
Conditions:
Healthy
Eligibility:
All Genders
25-50 years
Phase:
PHASE1
Brief Summary
To compare the physiological and psychological effects of psilocin taken orally by pill or sublingually by dissolving a tablet under the tongue to those of psilocybin taken by pill in healthy adults.
Detailed Description
The primary goal of this study is to compare the physiological and psychological effects of psilocin taken orally by pill or sublingually dissolved under the tongue to those of psilocybin taken by pil...
Eligibility Criteria
Inclusion
- Age 25 to 50
- Comfortable speaking and writing in English
- Commit to attending all study visits and remote data collection tasks
- No planned surgeries during the study
- Had at least one prior experience with a psychedelic substance
- Generally mentally and physically healthy
- Agree to abstain from THC, CBD, or nicotine products during study
Exclusion
- Participated in another clinical trial within 30 days of entry to this trial
- Regular use of medications that may have problematic interactions with psilocybin, including but not limited to dopamine agonists, MAO inhibitors, N-methyl-D-aspartate (NMDAR) antagonists, antipsychotics, and stimulants
- A health condition that makes study unsafe or unfeasible, determined by study physicians
Key Trial Info
Start Date :
May 26 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05317689
Start Date
May 26 2022
End Date
July 1 2025
Last Update
June 10 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of California, San Francisco
San Francisco, California, United States, 94143