Status:

COMPLETED

Virus Interactions in the Respiratory Tract; a Cohort Study With Children

Lead Sponsor:

UMC Utrecht

Conditions:

Respiratory Tract Infections

Coinfection

Eligibility:

All Genders

6-4 years

Brief Summary

Rationale: Prevention of virus induced acute respiratory infection (ARI) is a public health priority. As different respiratory virus infections can interact with each other, occurrence of one virus ma...

Eligibility Criteria

Inclusion

  • Age between 6 weeks and 4 years AND
  • 1\) have older siblings or 2) attend daycare. AND
  • Live within 30 minutes drive from UMCU (by car), have access to a fever thermometer and a freezer were biological samples can be temporarily stored

Exclusion

  • recurrent respiratory tract infections and are treated with antibiotic prophylaxis OR
  • known immunodeficiency OR
  • chronic lung disease that increases susceptibility to infection (e.g. cystic fibrosis) OR
  • congenital anomalies of the airways
  • Parents/guardians have insufficient comprehension of Dutch language (all study communication and questionnaires are in Dutch language)

Key Trial Info

Start Date :

September 15 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 23 2024

Estimated Enrollment :

229 Patients enrolled

Trial Details

Trial ID

NCT05318235

Start Date

September 15 2021

End Date

April 23 2024

Last Update

May 9 2024

Active Locations (1)

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UMC Utrecht

Utrecht, Netherlands, 3584 CX