Status:
RECRUITING
The Effect of Ketamine on Aesthetics and Role for Antidepressant Effects
Lead Sponsor:
Medical University of Vienna
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
Brief Summary
The aim of this study is to assess the impact of ketamine on aesthetic perception and processing. This study assesses the role of these effects in facilitating ketamine's antidepressant properties, wi...
Eligibility Criteria
Inclusion
- General health based on medical history and physical examination
- Psychiatric health based on structured clinical interview for DSM-5 (SCID) for healthy controls
- Major depressive episode (first or recurrent) based on structured clinical interview for DSM-5 and ICD-10 for patients
- Age 18 to 55 years
- Right-handedness (due to potential lateralization effects of lefthanded subjects)
- Willingness and competence to sign the informed consent form
Exclusion
- Current or history of neurological disease
- Current medical illness requiring treatment
- Psychiatric diagnosis for healthy individuals
- Psychiatric comorbidity with the exception of anxiety disorders for depressed individuals
- Pregnancy or current breastfeeding
- Current or former substance abuse
- Previous ketamine use in lifetime
- Any contraindication for MRI (e.g., MR incompatible implants, etc.) including dental implants causing signal artifacts
- Failure to comply with the study protocol or to follow the instruction of the investigating team
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 28 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05320107
Start Date
June 1 2022
End Date
February 28 2025
Last Update
April 15 2024
Active Locations (1)
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1
Medical University of Vienna
Vienna, Austria, 1090