Status:

RECRUITING

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

Lead Sponsor:

University of North Carolina, Chapel Hill

Collaborating Sponsors:

United States Department of Defense

Conditions:

Concussion, Brain

Eligibility:

All Genders

18-99 years

Phase:

NA

Brief Summary

The strategic objective of this research line is to examine improving short- and long-term outcomes for soldiers following mild traumatic brain injury (mTBI). The technical objectives are to: 1) condu...

Detailed Description

The study population will be soldiers stationed at Fort Bragg, North Carolina. Allocation to arm will be determined by time (preintervention/current practice (Group 1) vs. intervention/Active Rehab (G...

Eligibility Criteria

Inclusion

  • Current active duty military personnel stationed at Fort Bragg, North Carolina.
  • Report to clinic/provider at Fort Bragg and available for recruitment within 2 weeks of mTBI injury date as indicated in medical record.
  • Initial provider diagnosis of mTBI/concussion within 2 weeks of injury, confirmed via medical record.

Exclusion

  • Third mTBI/concussion in the past 12 months as indicated by the medical record and/or participant self-report.
  • Symptoms clear at rest and exertion within 48 hours as indicated in medical record and or during study enrollment process.
  • Moderate-Severe TBI, or TBI not meeting the criteria for mTBI as indicated by provider diagnosis.
  • Polytrauma or other injuries preventing completion of initial study assessments in the 2-week window as indicated in initial screening/medical record.
  • TBI, per the funding opportunity announcement is defined as: "being caused by (1) a direct blow or impact to the head, (2) a penetrating head injury, or (3) an exposure to external forces such as blast waves that disrupt the function of the brain." For the proposed study, only those meeting the VA/Department of Defense severity criteria of mild (normal structural imaging, loss of consciousness 0-30 minutes, alteration of consciousness or mental state up to 24 hours, posttraumatic amnesia up to 24 hours, and Glasgow Coma Scale of 13-15) will be targeted.

Key Trial Info

Start Date :

June 4 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT05320822

Start Date

June 4 2024

End Date

September 1 2026

Last Update

January 28 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

United States Special Operations Command

Fort Liberty, North Carolina, United States, 28310

2

Womack Army Medical Center

Fort Liberty, North Carolina, United States, 28310