Status:
COMPLETED
Tranexamic Acid During Telescoping Nail Application In Osteogenesis Imperfecta
Lead Sponsor:
Assiut University
Conditions:
Osteogenesis Imperfecta
Eligibility:
All Genders
Phase:
NA
Brief Summary
The aim of this study is to assess the effective of intraoperative use of tranexamic acid in reducing blood loss during telescoping nail application in cases of osteogenesis imperfecta.
Detailed Description
Osteogenesis imperfecta (OI) is a rare inherited pathology that consists of abnormal type one collagen synthesis that affects all structures in the body. The most important and early sign of this path...
Eligibility Criteria
Inclusion
- All patients with osteogenesis imperfecta who will undergo telescoping femoral nail application in Assiut University Hospital - Department of Orthopaedic and Trauma Surgery between April 2022 and March 2023.
Exclusion
- Known allergy to Tranexamic Acid
- History of any acquired disturbances of colour vision
- History of major comorbidities (e.g., severe ischemic heart disease)
- Refusal of blood products
- History of fibrinolytic disorders requiring intraoperative antifibrinolytic treatment, coagulopathy in the past and/or as identified by a preoperative platelet count of \<150,000/mm3, or a prolonged partial thromboplastin time, active intravascular clotting \& known congenital thrombophilia
- Preoperative use of anticoagulant therapy within five days before surgery
- Medical Unfit
- Participation in another clinical trial involving pharmaceutical drugs.
- Patients or their relatives who refuse to participate in the study
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05321199
Start Date
May 1 2022
End Date
November 30 2023
Last Update
December 14 2023
Active Locations (1)
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1
Assiut University Hospitals
Asyut, Egypt