Status:

RECRUITING

Resting State Changes Following Theta Burst Stimulation

Lead Sponsor:

Nicholas Balderston, PhD

Conditions:

Brain Connectivity

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Transcranial magnetic stimulation (TMS) is increasingly being applied to effectively treat mental illness, however efforts to quantify the effects of TMS on the network architecture of the brain have ...

Detailed Description

Transcranial magnetic stimulation (TMS) is currently approved by the FDA for the treatment of depression, obsessive compulsive disorder, and smoking cessation. Despite evidence that TMS improves sympt...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Able to give their consent
  • Right-handed
  • Exclusion Criteria
  • Non-english speaking
  • Any significant medical problems
  • Current or past Axis I psychiatric disorder(s),
  • Active or history of active suicidal ideation
  • Alcohol/drug problems in the past year or lifetime alcohol or drug dependence
  • Medications that act on the central nervous system
  • History of seizure
  • History of epilepsy or other neurological problems
  • Increased risk of seizure for any reason
  • Pregnancy
  • Any medical condition that increases risk for fMRI or TMS
  • Any metal in their body which would make having an MRI scan unsafe
  • Any sort of medical implants
  • Claustrophobia

Exclusion

    Key Trial Info

    Start Date :

    November 17 2022

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    August 1 2027

    Estimated Enrollment :

    200 Patients enrolled

    Trial Details

    Trial ID

    NCT05322239

    Start Date

    November 17 2022

    End Date

    August 1 2027

    Last Update

    January 7 2026

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    University of Pennsylvania

    Philadelphia, Pennsylvania, United States, 19104