Status:
UNKNOWN
Almonds and Cognitive Functions
Lead Sponsor:
Diabetes Foundation, India
Collaborating Sponsors:
National Diabetes Obesity and Cholesterol Foundation
Almond Board of California
Conditions:
PreDiabetes
Eligibility:
All Genders
40-60 years
Phase:
NA
Brief Summary
Initial Recruitment and Sensitization: In this free-living randomized control parallel arm study of 24 weeks of almond intervention, we shall recruit apparently healthy middle aged (age range 40-60 ye...
Detailed Description
Objectives and Measurements: a. Primary Objective: To evaluate the effect of almond supplementation on cognitive functions Co-primary Objective: To evaluate changes in neuroimaging (blood flow, and t...
Eligibility Criteria
Inclusion
- Asian Indians having fasting blood glucose ≥100mg/dl and \<126 mg/dl and /or 2-h plasma glucose ≥140mg/dl and \<200mg/dl (after ingestion of 75-gram anhydrous oral glucose)
- age 40-60 years
Exclusion
- Subjects Having Inability to Undergo Neuropsychological Testing
- Previously Diagnosed Neurodegenerative Disease Prior Stroke
- Significant Head Trauma, or Brain Surgery
- Relevant Psychiatric Illness
- Major Depression
- Morbid Obesity
- Diabetes
- Uncontrolled Hypertension
- Prior Chemotherapy
- Allergy to Almonds
- Habitual Consumption of Tree nuts (\>2 Servings/Wk.); or Customary Use Of Fish Oil, Flaxseed Oil, and/ Or Soy Lecithin
- Chronic Smoking
- Alcohol abuse (\> 2 Drinks, 60 Ml Of Whisky Per Day)
- Severe Dyslipidemia (Total Cholesterol \> 300 Mg/Dl, Serum Triglycerides \> 500mg/Dl)
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 30 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05322304
Start Date
June 1 2022
End Date
August 30 2024
Last Update
February 16 2023
Active Locations (1)
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1
National Diabetes Obesity and cholesterol Foundation (NDOC)
Delhi, India, 110024