Status:
RECRUITING
Biobank and Brain Health in Bordeaux.
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Brain
Aging
Eligibility:
All Genders
55-80 years
Brief Summary
B cube is a new generation cohort to study the determinants and natural history of brain aging, using molecular epidemiology, in a representative sample (N=2000) of the general population from the age...
Detailed Description
Cognitive aging and associated pathologies, primarily dementia and its main cause Alzheimer's disease, are a major public health issue. Because of the under-diagnosis of dementia in the population and...
Eligibility Criteria
Inclusion
- For the main study:
- live in Bordeaux metropolitan area,
- be between 55 and 80 years old (included),
- selected in terms of socioeconomic level, according to a sampling strategy by age groups and income categories representative of the general population between 55 and 80 years of age
- be affiliated with the social security system,
- agree to take a blood sample for the biobank.
- For the MRI sub-study: be between 55 and 75 years old (included). Inclusion criteria for the immune response substudy: be 70 years of age or older or participate in the MRI study; agree to take a supplemental blood sample for this substudy.
Exclusion
- For the main study: persons under guardianship (or more generally under protection), unable to give consent to participate.
- For the MRI sub-study: have a contraindication to MRI examination (pacemaker, a valve prosthesis or any other internal electrical/magnetic device; history of neurosurgery or aneurysm; claustrophobia; presence of metal fragments in the eyes, brain or spinal cord).
Key Trial Info
Start Date :
March 22 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 22 2030
Estimated Enrollment :
2050 Patients enrolled
Trial Details
Trial ID
NCT05322343
Start Date
March 22 2022
End Date
March 22 2030
Last Update
August 11 2025
Active Locations (1)
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1
University Hospital of Bordeaux
Bordeaux, Bordeaux, France, 33300