Status:
RECRUITING
Pragmatic Randomised Trial of the ESC 0/1 Versus 0/3 Hour Troponin Pathway
Lead Sponsor:
Liverpool University Hospitals NHS Foundation Trust
Collaborating Sponsors:
northwest coast academic science network
Quidel Corporation
Conditions:
Acute Coronary Syndrome
Troponin
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary objective of this study is to assess the feasibility and impact of implementing the ESC 0-1 hour high sensitive troponin pathway in clinical practice and with specific reference to the 0-3...
Detailed Description
1. the investigators propose to compare 2 'gold standard' NICE recommended/ESC guideline-backed pathways; the accelerated 0-1 hour troponin clinical pathway versus the conventional 0-3-hour pathway, i...
Eligibility Criteria
Inclusion
- Chest pain with moderate or high suspicion chest pain (see chest pain evaluation chart at end) or any patient the clinician deems suspicious for myocardial ischaemia thus requesting a troponin sample (between daytime hours 0800hrs to 1800hrs)
- Presentation \<12 hours since onset of chest pain (or unknown duration)
- Age \>18 years of age
Exclusion
- ST elevation myocardial infarction (STEMI) infarct on the presenting electrocardiogram (ECG)
- Symptoms considered definitely non-cardiac
- Trauma
- Pregnancy
- Comorbid conditions requiring hospital admission
- Coronary artery bypass graft surgery (CABG) \<1 month
- coexistent clinical conditions likely to preclude follow-up.
Key Trial Info
Start Date :
December 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 10 2024
Estimated Enrollment :
3536 Patients enrolled
Trial Details
Trial ID
NCT05322395
Start Date
December 10 2021
End Date
November 10 2024
Last Update
March 5 2024
Active Locations (1)
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1
liverpool university Hospital nhs foundation trust
Liverpool, GB, United Kingdom, L186JR