Status:

COMPLETED

Effectiveness of Topical Olive Oil in Prevention and Management of Radiation Induced Oral Mucositis

Lead Sponsor:

Salma Hesham Elhoufi

Conditions:

Radiation Mucositis

Oral Mucositis (Ulcerative) Due to Radiation

Eligibility:

All Genders

25-65 years

Phase:

NA

Brief Summary

This research aims to investigate the effectiveness of topical olive oil application both clinically and biochemically as a suitable affordable treatment modality for prevention and management of radi...

Detailed Description

Twenty adult patients seeking radiotherapy treatment for head and neck cancer are to be selected. Patients meeting the eligibility criteria are to be equally and randomly allocated in 2 different grou...

Eligibility Criteria

Inclusion

  • Patients who are aged above 25 years up to 65 years.
  • Both genders are eligible.
  • Patients with head and neck cancer who are planned to receive radiotherapy either as postoperative (adjuvant after surgery) or definitive therapy.
  • Patients planned to receive radiotherapy treatment with a dose of 60-70 Gy.

Exclusion

  • Patients with known sensitivity to olive oil and/or any of its products
  • Patients with gingival or oral ulceration or mucositis
  • Smokers
  • Vulnerable patients (pregnant women, neonates, children, prisoners, persons with physical handicaps or mental disabilities)
  • Pregnant and lactating women.
  • Patients with any uncontrolled systemic diseases (such as diabetes, cardiovascular, liver disorder, renal dysfunction)
  • Patients suffering from any physical or mental disabilities that would interfere with or be affected by the study procedure.

Key Trial Info

Start Date :

January 10 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 15 2022

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05322421

Start Date

January 10 2022

End Date

December 15 2022

Last Update

August 2 2024

Active Locations (1)

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1

Salma Hesham Elhoufi

Cairo, Select, Egypt, 11571