Status:

ENROLLING_BY_INVITATION

Optimization of Exhaled Biomarker Collection and Analysis

Lead Sponsor:

Indiana University

Conditions:

Respiratory Disease

Healthy

Eligibility:

All Genders

4-110 years

Phase:

NA

Brief Summary

This is an exploratory study designed to optimize, standardize, and validate novel breath biomarkers; there are no objective endpoints. The goal of this study is to generate pilot data to be used to g...

Detailed Description

Exhaled breath has three fractions - gaseous breath, volatile breath, and breath condensate. Biomarkers have been identified in each of these fractions and non-invasive collection methods have been de...

Eligibility Criteria

Inclusion

  • Study sample will consist of individuals aged 4-110 with a diagnosis of acute or chronic respiratory disorders, or metabolic or systemic conditions involving diffuse inflammation, or normal subjects with no pulmonary disease.

Exclusion

  • Subjects that are unable or unwilling to cooperate with specimen collection.

Key Trial Info

Start Date :

February 2 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 31 2030

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT05322785

Start Date

February 2 2020

End Date

January 31 2030

Last Update

March 6 2025

Active Locations (1)

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1

Indiana University School of Medicine - Wells Center for Pediatric Research

Indianapolis, Indiana, United States, 46202