Status:
NOT_YET_RECRUITING
Urinary Continence of Female POPRC and OIN
Lead Sponsor:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Collaborating Sponsors:
Peking University Third Hospital
Conditions:
Urinary Bladder Neoplasms
Woman
Eligibility:
FEMALE
55-75 years
Phase:
NA
Brief Summary
To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectom...
Detailed Description
Radical cystectomy is the gold standard for muscle-invasive bladder. Orthotopic ileal neobladder, as one of the urinary diversion methods, is preferred whenever possible to achieve a better postoperat...
Eligibility Criteria
Inclusion
- Female patients aged between 55-75.
- Patients those who are diagnosed with organ-confined urothelial carcinoma（\<pT3）
- Patients those who are capable for radical cystectomy with orthotopic ileal neobladder.
- ECOG score between 0-2;
- Normal renal function;
- Patients those who volunteer to participate in this study and sign the informed consents.
- Patients those who are able to cooperate in the study.
Exclusion
- Absence of tumour in bladder neck or urethra;
- Patients thsoe who are diagnosed distant metastasis before surgery.
- Previous history of malignancy of pelvic organs or surgical resection of pelvic organs;
- Patients those who are diagnosed with other malignancies.;
- Patients those who had received pelvic radiotherapy or major pelvic operation.
- Pregnancy status;
- Any other conditions that the researcher considers to be excluded from this study
Key Trial Info
Start Date :
April 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2028
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT05325216
Start Date
April 1 2022
End Date
April 1 2028
Last Update
April 13 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Sun Yat-Sen Memorial Hospital
Guangzhou, Guangdong, China