Status:
UNKNOWN
Does Caffeine Facilitate Human Reward Learning Behaviors?
Lead Sponsor:
Yu-Shiuan Lin
Conditions:
Caffeine
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
"Learning from the rewards" is underlying the formulation of knowledge and habits in daily life. Caffeine is the most commonly used "psychoactive" substance that could change one's mind state by affec...
Detailed Description
Reward learning is associated with the formulation of habits, memories, and beliefs. Positive (receiving an unexpected reward) and negative reinforcement (eliminating an unwanted state) learning are p...
Eligibility Criteria
Inclusion
- Age ≥ 18 and ≤ 40
- Clinically healthy
- Non-smokers
Exclusion
- Habitual caffeine intake \< 100 mg or \> 450 mg
- Pregnant or lactating women
- Women using hormonal contraceptives
- BMI \< 18.5 or \> 29.9
- Sleep disturbance or extreme chronotypes
- Nicotine or recreational drug users
- Depression, anxiety, psychosis, or neurologic disorders
- Severe heart or cardiovascular diseases
- Diabetes or metabolic diseases
- Under chronic medications
- Incapable to operate the tasks or comprehend the study information in German or English
- Users of the Bopomo alphates utilized as stimuli in the reward learning tasks
- Current enrolment in other clinical trials
Key Trial Info
Start Date :
May 5 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT05325502
Start Date
May 5 2022
End Date
December 31 2024
Last Update
August 31 2023
Active Locations (1)
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1
Centre for Chronobiology, University Psychiatric Clinics Basel
Basel, Canton of Basel-City, Switzerland, CH-4002