Status:

COMPLETED

Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial

Lead Sponsor:

Department of Medical Services Ministry of Public Health of Thailand

Conditions:

Pain, Post Operative

Arthroplasty Complications

Eligibility:

All Genders

45-60 years

Phase:

NA

Brief Summary

This research aim to improve postoperative outcome in total hip arthroplasty(THA) by using local mixture infiltration as bupivacaine + NSAID + epinephrine + tranxemic acid. In the present time these m...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • patient who would go on cemented and cementless THA
  • age 45-60 years of age
  • voluntary decision exclusion criteria
  • bilateral THA
  • revision surgery
  • history of pelvic and hip surgery previously
  • allergy to medication in protocol
  • CKD stage 4-5, chronic liver disease with Child Pugh B or C
  • pregnancy
  • history of hip injection
  • U/D
  • hypercoagulable state
  • abnormal laboratory coagulation study as INR \> 1.4 or aPTT \> 1.4
  • abnormal platelet function
  • thrombocytopenia
  • PE , DVT, ischemic stroke, CAD/ischemic heart disease
  • use of anticoagulant or hormonal usage
  • anesthesia by general anesthesia or additional nerve block
  • can not understand PCA usage
  • use postopertive wound drainage

Exclusion

    Key Trial Info

    Start Date :

    April 5 2022

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    October 31 2023

    Estimated Enrollment :

    120 Patients enrolled

    Trial Details

    Trial ID

    NCT05325671

    Start Date

    April 5 2022

    End Date

    October 31 2023

    Last Update

    January 25 2024

    Active Locations (1)

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    1

    Rajavithi Hospital

    Bangkok, Thailand