Status:

RECRUITING

Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease

Lead Sponsor:

The University of Texas Health Science Center, Houston

Conditions:

Huntington Disease

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

The purpose of this study is to assess feasibility, acceptability, and safety of providing transcranial direct current stimulation( tDCS) to Huntingtons Disease (HD) patients in the early to middle st...

Eligibility Criteria

Inclusion

  • Participant:
  • confirmed HD mutation carriers
  • early (stages 1 and 2) or moderate (stage 3) stages according to Shoulson-Fahn
  • exhibit mild to moderate behavioral symptoms, such as clinically diagnosed apathy, irritability, anxiety, depression, aggression and repetition
  • stable doses of medications for at least one month

Exclusion

  • unstable medical conditions
  • history of epilepsy
  • metallic objects in the brain
  • clinical diagnosis of major cognitive disorder or dementia
  • Have risk of suicidal behavior, defined as any suicidal behavior or suicidal ideation of type 4
  • Caregiver:
  • Inclusion Criteria:
  • willingness to participate in the study

Key Trial Info

Start Date :

June 21 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT05326451

Start Date

June 21 2023

End Date

December 31 2026

Last Update

January 29 2025

Active Locations (1)

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1

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030