Status:
RECRUITING
NRP vs DHOPE vs COR-NMP in ECD-DCD Donation
Lead Sponsor:
Erasmus Medical Center
Collaborating Sponsors:
University Medical Center Groningen
Leiden University Medical Center
Conditions:
Liver Transplant
Organ Perfusion
Eligibility:
All Genders
50-75 years
Brief Summary
There is still a discrepancy between the number of liver transplant candidates and the availability of liver grafts, resulting in waiting list mortality. To increase the supply of suitable liver graft...
Detailed Description
The persistent discrepancy between the number of patients awaiting liver transplant and the availability of liver grafts. In the Netherlands, still, 1 in 5 either dies on the waiting list or is remove...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- DCD donor (Maastricht type III and V)
- Age above 50 years old and below 75 years old
- Exclusion criteria:
- Malignancy (except for primary non-metastatic central nervous system tumors, non-melanoma skin tumors or cured malignancies)
- Active infection (sepsis, meningitis, human immune deficiency virus, rubella, rabies, herpes zoster, tuberculosis)
- Intravenous drug abuse
- Unknown cause of death
- In the case of a NRP procedure: donors with a BMI above 35 and transaminases above 1000 U/I and not decreasing prior to donation are excluded
Exclusion
Key Trial Info
Start Date :
January 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2029
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05327478
Start Date
January 1 2022
End Date
May 1 2029
Last Update
April 14 2022
Active Locations (1)
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1
Erasmus MC
Rotterdam, South Holland, Netherlands