Status:
UNKNOWN
Targeting Microbiota in Female Overactive Bladder Syndrome
Lead Sponsor:
Medical University of Vienna
Conditions:
Microbiota
Urinary Bladder, Overactive
Eligibility:
FEMALE
18+ years
Brief Summary
The aim of this study is to compare the urinary viral microbiome and bacterial microbiome between overactive bladder syndrome (OAB) patients and healthy controls in order to determine a possible alter...
Eligibility Criteria
Inclusion
- Inclusion Criteria (case group):
- symptoms of overactive bladder (urgency with or without urinary leakage, usually with frequency and nocturia)
- Exclusion Criteria (case group):
- Pregnant or lactating females
- Neurological conditions (such as MS, Parkinson, spinal cord injury, stroke..)
- Pelvic Organ Prolapse (stage ≥ 3)
- Lower Urinary Tract surgery within past 6 months
- Known history of interstitial cystitis or pain associated with OAB
- Recurrent urinary tract infections \> 3/year
- Acute urinary tract infection
- Urinary retention (with or without required self- catheterization)
- Stress urinary incontinence or mixed urinary incontinence
- Bladder cancer
- Renal insufficiency
- Urinary tract stones
- Inclusion Criteria (control group):
- without symptoms of overactive bladder or any other form of lower urinary tract symptoms
- Age-matched to case group (+/- 5 years)
- BMI-matched to case group (18,5- 24,9 kg/m2 normal weight; 25- 29,9 kg/m2 overweight; 30- 34,9 kg/m2 obesity grade I)
- Exclusion criteria (control group):
- As case group plus any form of lower urinary tract symptoms including OAB
Exclusion
Key Trial Info
Start Date :
December 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05328011
Start Date
December 1 2020
End Date
November 30 2024
Last Update
April 14 2022
Active Locations (1)
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1
Medical University of Vienna
Vienna, Austria, 1090