Status:
COMPLETED
Characterization of Intestinal Microbiota in Children With Inborn Errors of Metabolism (IEM)
Lead Sponsor:
Emma Marie Caroline Slack
Collaborating Sponsors:
University Children's Hospital
Conditions:
Inborn Errors of Metabolism
Propionic Aciduria
Eligibility:
All Genders
Up to 18 years
Brief Summary
Study around children with inborn errors of metabolism (IEM) and their healthy siblings. Collection of stool and urine to assess contribution of microbiota to disease severity.
Detailed Description
This study aims to collect biological samples (stool and urine) from children with inborn errors of metabolism, IEM (like UCD (urea cycle disorder), PA (propionic aciduria) and MMA (methylmalonic acid...
Eligibility Criteria
Inclusion
- Children or siblings of children that have been diagnosed with one of the following diseases: any type of UCD, PA or MMA
Exclusion
- Children or siblings of children that have not been diagnosed with one of the following diseases: any type of UCD, PA or MMA
- use of an investigational drug or device less than 30 days prior to the study, or current enrollment in another investigational drug or device study less than 30 days prior to the study
- considered to be poor attendees or unlikely for any reason to be able to comply with the study procedures, in the opinion of the investigator
Key Trial Info
Start Date :
November 30 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 27 2024
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT05330039
Start Date
November 30 2021
End Date
February 27 2024
Last Update
March 1 2024
Active Locations (1)
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1
University Children's Hospital
Zurich, Switzerland, 8032