Status:
ACTIVE_NOT_RECRUITING
Genetics of Ventriculo-arterial Discordance
Lead Sponsor:
Nantes University Hospital
Collaborating Sponsors:
Inserm UMR1087, CNRS UMR6291
Clinique des Données, CIC 1413, CHU Nantes
Conditions:
Heart Defects, Congenital
Eligibility:
All Genders
1-100 years
Phase:
NA
Brief Summary
Number of centres planned : 16 centres in France Type of study / Study design : Research Involving the Human Person category 2. Multicentric. Prospective Planning of the study : Total duration: 57,...
Eligibility Criteria
Inclusion
- Patients with transposition of the great arteries or transposition congenitally corrected of the great arteries with healthy parents and no family history of congenital heart disease (familial trio)
- Or patients with transposition of the great arteries or transposition congenitally corrected of the great arteries with or without a history of congenital heart disease (familial form or sporadic case)
- Affiliated or beneficiaries of a social security scheme or similar
- After obtaining oral consent from patients and/or parents if applicable
- Parents (for family trios) :
- \- Biological parents of the child included in the PRECIPED study
Exclusion
- Patients with transposition of the great arteries or transposition congenitally corrected of the great arteries with hypoplastic ventricle or atrioventricular and/or ventriculoarterial valve atresia
- Patient with an identified malformation syndrome
- Patients under guardianship/curatorship
- Patients with State Medical Aid
- Refusal of consent by the patient and/or one of the two parents
Key Trial Info
Start Date :
September 7 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 24 2027
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT05330338
Start Date
September 7 2022
End Date
June 24 2027
Last Update
December 11 2025
Active Locations (16)
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1
CHU Marseille
Marseille, Bouches-du-Rhône, France, 13000
2
CHU Rennes
Rennes, Brittany Region, France, 35000
3
CHU Bordeaux
Bordeaux, Gironde, France, 33000
4
CHU Toulouse
Toulouse, Haute-Garonne, France, 31000