Status:

TERMINATED

Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation

Lead Sponsor:

University of Iowa

Conditions:

Tooth Extraction

Immediate Implant Placement

Eligibility:

All Genders

18-95 years

Phase:

NA

Brief Summary

Mid-facial recession following immediate implant placement (IIP) in the place of a tooth poses a significant challenge for clinicians to treat. Emerging evidence shows that connective tissue graft (CT...

Eligibility Criteria

Inclusion

  • Age 18-95
  • Has a single hopeless tooth in the maxillary esthetic zone (i.e., first premolar to first premolar, tooth #5-tooth #13)
  • Adequate oral hygiene (i.e., full-mouth bleeding score (FMBS) and full mouth plaque score (FMPS) of less than 25%)
  • Adequate tooth space to support an immediate implant placement (i.e., adequate mesiodistal space of greater than or equal to 6 mm and interocclusal space to support a non-occluding provisionalization).
  • Postextraction vertical bone defect of the buccal socket wall was less than or equal to 3mm.

Exclusion

  • patients taking long-term (more than 3 months) medications affecting bone metabolism
  • generalized untreated periodontitis with greater than of 30% of sites with greater than 5mm pocket depths and bleeding upon probing with a dental probe
  • medical contraindications for having a surgical procedure (i.e., ASA Status of III, patient with a severe systemic disease that is not life-threatening; ASA Status of IV, a patient with a severe systemic disease that is a constant threat to life).
  • history of radiotherapy in the head and neck region
  • heavy smoker (greater than 10 cigarettes per day)
  • pregnancy
  • gingival recession before extraction in relation to the contralateral tooth.

Key Trial Info

Start Date :

January 17 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 4 2024

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT05330702

Start Date

January 17 2023

End Date

March 4 2024

Last Update

October 29 2025

Active Locations (1)

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1

University of Iowa College of Dentistry and Dental Clinics

Iowa City, Iowa, United States, 52242