Status:
RECRUITING
Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane on Long-term Outcomes With Patients Undergoing Elective Excision of Primary Liver Tumors
Lead Sponsor:
Kaohsiung Medical University Chung-Ho Memorial Hospital
Collaborating Sponsors:
Tri-Service General Hospital
Conditions:
Hepatocellular Carcinoma
Eligibility:
All Genders
20-80 years
Phase:
PHASE4
Brief Summary
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary Hepatocellular carcinoma. The study will enroll approximately 500 ...
Detailed Description
Before the scheduled procedure, the patients are randomly assigned into peopofol group or groups (1:1) according to the randomization generated by the computer. Both groups were induced with propofol ...
Eligibility Criteria
Inclusion
- Twenty to eighty-year-old.
- ASA class I-III.
- Patients undergoing partial hepatectomy for hepatocellular carcinoma under general anesthesia.
Exclusion
- Severe mental disorder
- Pregnant or lactating women
- Morbidly obese
- Allergy to any of the drugs used in this study
- Recurrent tumor or repeat surgery
- Biopsy cases
- Incomplete data collection before the surgery
- Palliative treatment after surgery
- simultaneous treatment of other malignancies
- Combined propofol and inhalation anesthesia or other anesthetics, such as ketamine or dexmedetomidine
- Diagnosed as benign liver tumor
- Emergency surgery
Key Trial Info
Start Date :
April 26 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2027
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT05331911
Start Date
April 26 2022
End Date
March 31 2027
Last Update
November 30 2022
Active Locations (1)
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1
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Taiwan