Status:
RECRUITING
MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy
Lead Sponsor:
Centre Hospitalier Universitaire de Besancon
Conditions:
Cutaneous T-Cell Lymphoma
Graft Vs Host Disease
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The objective of this study is to describe the type of cell death induced by extracorporeal photochemotherapy, depending on the cell type, using a panel of complementary analysis techniques.
Detailed Description
Extracorporeal photochemotherapy (ECP) is a cell therapy used for its immunomodulation and tolerance induction capabilities. Its main indications are the control of graft-versus-host (GVH) disease in ...
Eligibility Criteria
Inclusion
- Adult patients
- Treated with ECP for at least 1 month, for control of GVHD in hematopoietic cell allograft (acute or chronic GVHD), treatment and control of cellular or humoral rejection in solid organ transplantation (heart, lung, kidney) or in the treatment of cutaneous T-cell lymphoma
Exclusion
- Subjects with limited legal capacity.
- Subjects judged by the investigator to be unlikely to comply with study procedures
- Subjects with no social security coverage.
- Pregnant women.
- Subjects still in the exclusion period of another study, or according to the national registry of clinical trial participants.
Key Trial Info
Start Date :
April 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05333367
Start Date
April 15 2022
End Date
July 1 2025
Last Update
November 21 2024
Active Locations (1)
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1
Centre Hospitalier Universitaire de Besançon
Besançon, France, 25000