Status:

RECRUITING

Reducing Pain From Wisdom Molar Extractions

Lead Sponsor:

Rutgers, The State University of New Jersey

Conditions:

Acute Pain

Eligibility:

All Genders

18-64 years

Phase:

PHASE2

Brief Summary

This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergo...

Detailed Description

Each year, over 3.5 million, mostly, healthy young adults, have their third molar teeth ('wisdom teeth') removed under sedation and are often given opioid prescriptions for managing their pain. Wisdom...

Eligibility Criteria

Inclusion

  • Age 18 years of age or older (up to 64 years)
  • Any demographic
  • ASA 1 and 2 (mild or absent systemic illnesses, deemed fit for undergoing dental extractions under intravenous sedation)
  • Not pregnant (as will not qualify to undergo procedure under intravenous sedation as part of routine standard-of-care)
  • Adequate mental ability to understand and provide informed consent
  • Has smart phone and internet connection

Exclusion

  • Age older than 64 years (because they are poor candidates for undergoing procedures under intravenous sedation)
  • Pregnant
  • Incapable of providing informed consent
  • Any systemic condition that renders the patient at higher risk for complications under intravenous sedation
  • Documented allergy to the dental local anesthetic
  • Inability to tolerate any of the commonly used pain medications such as combination opioids, acetaminophen (Tylenol®) or ibuprofen (Motrin® or Advil®)
  • Limitation in adequate mouth opening in presence/absence of pain

Key Trial Info

Start Date :

September 13 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05335070

Start Date

September 13 2022

End Date

December 1 2026

Last Update

December 5 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

The University Hospital- Dental Clinic

Newark, New Jersey, United States, 07103