Status:
RECRUITING
Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
Lead Sponsor:
University Hospital Freiburg
Collaborating Sponsors:
Charite University, Berlin, Germany
Johann Wolfgang Goethe University Hospital
Conditions:
HNSCC
Oral Cavity Cancer
Eligibility:
All Genders
65+ years
Brief Summary
The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often vulnerable and frail patient cohort is li...
Eligibility Criteria
Inclusion
- definitive (chemo-)radiotherapy of locoregionally advanced (cT3-4 and/or cN+) head-and-neck squamous cell carcinomas (HNSCC) of the oral cavity, oropharynx, hypopharynx or larynx
- primary treatment since 2005
- age ≥65 years at the time of (chemo-)radiotherapy
Exclusion
- adjuvant (chemo-)radiotherapy
- history of previous head-and-neck cancers or radiotherapy in the head-and-neck region
- distant metastases at (chemo-)radiotherapy initiation (cM1)
- HNSCCs of the nasopharynx, salivary glands, skin or with unknown primary
Key Trial Info
Start Date :
June 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT05337631
Start Date
June 1 2021
End Date
December 31 2026
Last Update
March 25 2025
Active Locations (18)
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1
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine
Baltimore, Maryland, United States, 21287
2
Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10017
3
Department of Radiation Oncology, Case Western Reserve University
Cleveland, Ohio, United States, 10900
4
Division of Radiation Oncology, The Ohio State University Wexner
Columbus, Ohio, United States, 43201