Status:

COMPLETED

Efficacy of Generic Pegfilgrastim vs Brand Name Pegfilrastim for Neutrophil Recovery After Autotransplant

Lead Sponsor:

Hospital Universitario Dr. Jose E. Gonzalez

Conditions:

Myeloma Multiple

Lymphoma

Eligibility:

All Genders

18-90 years

Phase:

PHASE2

Brief Summary

This is a phase 2 clinical trial comparing time to neutrophil recovery after autotrasplant using generic pegfilgrastim vs brand-name pegfilgrastim.

Detailed Description

Thirty consecutive adults with lymphoma or myeloma receiving autologous peripheral blood stem cell transplant will be included in this phase 2 clinical trial. Patients will be allocated 1:1 in two gro...

Eligibility Criteria

Inclusion

  • Patients undergoing autologous peripheral blood stem cell transplantation
  • Patients with multiple myeloma or lymphoma
  • Adults (\>18 years)
  • Both genders
  • Eastern Cooperative Oncology Group (ECOG) \<=2

Exclusion

  • Alanine Aminotransferase or bilirubin values \>2.5 times the superior normal limit
  • Creatinin \>2.2mg/dL
  • Fever \>37.6°C
  • Active infection
  • Hepatitis B, C or HIV infection
  • Congestive heart failure (ejection fraction \<40%)

Key Trial Info

Start Date :

April 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 25 2023

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05338047

Start Date

April 1 2022

End Date

February 25 2023

Last Update

February 28 2023

Active Locations (1)

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1

Hospital Universitario Dr. José Eleuterio González

Monterrey, Nuevo León, Mexico, 66260