Status:
UNKNOWN
Effect of Exogenous Growth Hormone on Ocular Findings
Lead Sponsor:
Isfahan University of Medical Sciences
Conditions:
Precocious Puberty
Early Puberty
Eligibility:
All Genders
4-11 years
Brief Summary
Body size and eye function play an essential role in adapting to the environment and human survival. Growth hormone is commonly recognized by its effect on the height of individuals; Although from an ...
Detailed Description
Investigators will achieve the following data from the participants: 1. Demographics 2. Past medical history 3\. Bone and calendar age 4- Stage of puberty 5- Ocular examination 6\. Ocular biometr...
Eligibility Criteria
Inclusion
- Sample group (with early or precocious puberty):
- Children with precocious puberty based on Tanner classification
- Girls 4 to 10 years old
- Boys aged 4 to 11
- No known eye problems including: history of eye trauma, eye surgery 5- lack of family history of glaucoma or increased intraocular pressure
- 6\. Lack of previous history of receiving growth hormone 7. Lack of systemic disease or known syndromes 8. Consent to participate in the study
Exclusion
- Incidence of growth hormone adverse reactions leading to discontinuation of treatment
- Changing the patient's treatment plan during the study
- Ocular complications requiring treatment during the study
- Unwillingness of the patient to continue participating in the study
Key Trial Info
Start Date :
March 20 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 22 2023
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05338411
Start Date
March 20 2022
End Date
October 22 2023
Last Update
April 21 2022
Active Locations (2)
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1
Isfahan University of Medical Sciences
Isfahan, Iran, +98
2
Isfahan Eye Research Center
Isfahan, Iran, 81746-73461