Status:

ACTIVE_NOT_RECRUITING

Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial

Lead Sponsor:

Roswell Park Cancer Institute

Conditions:

Head and Neck Squamous Cell Carcinoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This clinical trial compares intensive symptom evaluation with supportive care to standard symptom management in patients with head and neck cancer that has not spread to other places in the body (non...

Detailed Description

PRIMARY OBJECTIVE: I. Using study questionnaires to determine the impact of intensive symptom evaluation with supportive care as needed per treating physician's discretion versus standard symptom man...

Eligibility Criteria

Inclusion

  • PATIENTS: Age \>= 18 years of age
  • PATIENTS: Diagnosed with biopsy-proven, non-metastatic squamous cell carcinoma of head and neck
  • PATIENTS: Scheduled to start curative-intent radiation therapy within 4 weeks
  • PATIENTS: Able to provide informed consent in English
  • PATIENTS: Able to read and write in English
  • PATIENTS: Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related assessment
  • PATIENTS' INFORMED CAREGIVER (e.g. family members, friends): They are verbally identified by eligible patients as a caregiver
  • PATIENTS' INFORMED CAREGIVER (e.g. family members, friends): They are not receiving any payment to provide care for patients
  • PATIENTS' INFORMED CAREGIVER (e.g. family members, friends): Able to provide informed consent in English
  • PATIENTS' INFORMED CAREGIVER (e.g. family members, friends): Able to read and write in English

Exclusion

  • PATIENTS: Diagnosed with metastatic head and neck cancer
  • PATIENTS: Eligible for palliative-intent radiation therapy only
  • PATIENTS: Pregnant female participants
  • PATIENTS: Unwilling or unable to follow protocol requirements
  • PATIENTS: Any condition which in the Investigator's opinion deems the participant an unsuitable candidate

Key Trial Info

Start Date :

October 11 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 25 2026

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT05338905

Start Date

October 11 2022

End Date

August 25 2026

Last Update

October 2 2025

Active Locations (1)

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1

Roswell Park Cancer Institute

Buffalo, New York, United States, 14263

Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial | DecenTrialz