Status:
RECRUITING
Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients
Lead Sponsor:
Central Hospital, Nancy, France
Conditions:
Epilepsy, Temporal Lobe
Cognitive Decline
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Anterior temporal epilepsy is the most frequent form of focal epilepsy (more than 50% of focal epilepsies). The epilepsy is drug-resistant when epileptic seizures persist despite antiepileptic treatme...
Eligibility Criteria
Inclusion
- Adult person,
- Person affiliated to a social security scheme or beneficiary of such a scheme,
- Person having received complete information on the organization of the Clinical Investigation and having signed informed consent,
- Person having carried out a preliminary clinical examination adapted to the Clinical Investigation,
- For patients: Person with drug-resistant structural focal epilepsy of the anterior temporal lobe (right or left), candidate for epilepsy surgery (anterior temporal lobectomy),
- For healthy volunteers: Person with no known pathology in the anterior temporal lobe (particularly epilepsy).
Exclusion
- Contraindication to MRI including claustrophobia,
- Uncorrected visual disturbances,
- Person unable to give consent,
- Lack of mastery of the French language or ability to understand instructions,
- Person referred to in Articles 64, 65 and 66 of European Regulation 2017/745: Person of full age unable to consent alone to participate in the Clinical Investigation; Minor; Pregnant or breastfeeding woman.
Key Trial Info
Start Date :
June 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 9 2027
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05339438
Start Date
June 10 2022
End Date
June 9 2027
Last Update
July 1 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Centre Hospitalier Régional Universitaire de Nancy
Nancy, France