Status:

COMPLETED

Long Term Bowel Function Following Rectal Cancer Surgery

Lead Sponsor:

Mansoura University

Conditions:

Bowel; Functional Syndrome

Rectal Cancer

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

* In this longitudinal study, 171 patients were evaluated and compared based on the radiation therapy they received. * Bowel function was assessed longitudinally with Memorial Sloan Kettering Cancer C...

Detailed Description

Background Despite advances in the neoadjuvant chemoradiation therapy and anal sphincter-preserving surgeries for rectal cancer, bowel dysfunction is still unavoidable which negatively affect the pati...

Eligibility Criteria

Inclusion

  • Patients of both sexes,
  • Aged between 18 and 75 years,
  • Patients with mid and upper rectal cancer (6-15) cm from the anal verge(AV) with or without preoperative chemo radiotherapy.
  • Patients who underwent low anterior resection(LAR).
  • Patients who were followed up with at least two outpatient visits for bowel function assessment.

Exclusion

  • Patients with recurrent rectal tumors,
  • Surgically unfit patients,
  • Patients with tumors infiltrating the puborectalis muscle or external sphincter.
  • Patients with preoperative fecal incontinence.
  • Patients who were followed up only once in the outpatient clinic.
  • Patients with lower rectal cancer less than 6cm from AV,
  • Patients who underwent abdominoperineal resection(APR) or intersphincteric resection(ISR).

Key Trial Info

Start Date :

August 12 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 25 2020

Estimated Enrollment :

171 Patients enrolled

Trial Details

Trial ID

NCT05339763

Start Date

August 12 2019

End Date

February 25 2020

Last Update

April 21 2022

Active Locations (1)

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1

Ahmad

Al Mansurah, Egypt