Status:
COMPLETED
Effect of Octreotide on Saliva
Lead Sponsor:
Duke University
Conditions:
Healthy
Eligibility:
All Genders
18-40 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine the effect of Octreotide on saliva enzymes. The study team hypothesizes that Octreotide will decrease the levels of certain proteins, specifically the metallo...
Detailed Description
This is a healthy volunteer pilot study. The purpose of this study is to determine the effect of a drug, Octreotide, on saliva enzymes in order to see if this drug can help prevent pharyngo-cutaneous ...
Eligibility Criteria
Inclusion
- Healthy adults between the ages of 18-40 years old
- Healthy volunteer who is willing to undergo research activities
- Healthy volunteer with no self-report of disease, oral symptoms or lesions, or cold or flu like symptoms that would affect the reflective measurements in the oral cavity
- Ability to understand and the willingness to sign a written informed consent document
Exclusion
- Pregnant or nursing women
- Children under the age of 18 or adults over 40
- Complaint of oral symptoms (self-reported)
- Medical condition affecting saliva (e.g. Sjogren's)
- History of head/neck radiation
- Medication that might affect saliva (e.g. Proton Pump Inhibitors)
- Known allergy to Octreotide
- Non-English speaking
- Diabetes, gallbladder disease, heart disease, high blood pressure, a heart rhythm disorder, thyroid problems, pancreatitis, kidney disease, or liver disease (self-reported)
Key Trial Info
Start Date :
September 24 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 26 2020
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT05340192
Start Date
September 24 2019
End Date
February 26 2020
Last Update
April 22 2022
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27710