Status:

UNKNOWN

Investigating the Effects of Hydroxyvitamin D3 on Multiple Sclerosis

Lead Sponsor:

Tehran University of Medical Sciences

Collaborating Sponsors:

Boston University

Conditions:

Multiple Sclerosis, Relapsing-Remitting

Adult ALL

Eligibility:

All Genders

18-55 years

Phase:

PHASE4

Brief Summary

Investigating the effects of hydroxyvitamin D3 on clinical, radiologic and immunomodulatory markers in MS patients: A randomized, clinical trial- a pilot study

Detailed Description

Vitamin D deficiency/insufficiency is a risk factor for developing MS and is linked to increased disease activity in those with established disease. Several clinical trials have already been conducted...

Eligibility Criteria

Inclusion

  • MS type: relapsing-remitting MS (RRMS)
  • older than 18 year-old
  • Vitamin D deficiency/insufficiency (25(OH)D\<30 ng/ml

Exclusion

  • medications or disorders that would affect vitamin D metabolism
  • history of other chronic disorders
  • history of conditions that could lead to high serum calcium levels
  • pulse therapy in the last 3 months
  • history of attack in the last 3 months
  • using corticosteroid in the last 3 months
  • be pregnant

Key Trial Info

Start Date :

July 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2023

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT05340985

Start Date

July 1 2022

End Date

December 1 2023

Last Update

April 22 2022

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Investigating the Effects of Hydroxyvitamin D3 on Multiple Sclerosis | DecenTrialz