Status:
COMPLETED
Ketamine Versus Dexmedetomidine for Prevention of Postoperative Delirium
Lead Sponsor:
Huda Fahmy Mahmoud, PhD
Conditions:
Emergence Delirium
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
Delirium is a common postoperative complication in the elderly, often caused by multiple factors. It is defined as an acute neuropsychiatric disorder characterized by fluctuating disturbances in atten...
Detailed Description
Over the last few decades, numerous risk factors for delirium have been identified, emphasizing the importance of delirium prevention in patients undergoing surgery. It has already been identified as ...
Eligibility Criteria
Inclusion
- 1- Patients aged ≥ 65 years. 2- Scheduled for visceral, orthopedic, vascular, obstetric, urology, or plastic surgery.
Exclusion
- 1- Delirium upon hospital admission or development of delirium prior to surgery stated by family members.
- 2- Mini-Mental State Examination (MMSE) score \< 24 points 3- Delirium Observation Scale (DOS) ≥4 points 4- preoperative neurological diseases affecting cognitive function (such as vascular dementia) 5- High risk for postoperative treatment in the intensive care unit (ICU) 6- Known to have dexmedetomidine and or ketamine intolerance. 7- Lack of cooperation or communication. 8- Parkinson's disease, parkinsonism, intake of dopaminergic drugs (levodopa, dopamine agonists) 9- Epilepsy. 10- Patients on steroid therapy 11- severe liver and renal insufficiency
Key Trial Info
Start Date :
December 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 6 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05341154
Start Date
December 1 2021
End Date
May 6 2023
Last Update
May 9 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Huda Fahmy Mahmoud
Aswān, Egypt, 81511