Status:

COMPLETED

Effects of Thoracic Paravertebral Block Combined With S-ketamine on Postoperative Pain and Cognitive Function After Thoracoscopic Surgery

Lead Sponsor:

The First Hospital of Qinhuangdao

Conditions:

Postoperative Cognitive Dysfunction

Eligibility:

All Genders

45-65 years

Phase:

NA

Brief Summary

To investigate the effect of ultrasound-guided thoracic paravertebral nerve block combined with intraoperative infusion of s-ketamine on postoperative acute pain and cognitive function in patients wit...

Detailed Description

A total of 120 patients who were admitted to Qinhuangdao First Hospital for and divided into control group (group C ), thoracic paravertebral nerve block combined with full Anesthesia group (group TA)...

Eligibility Criteria

Inclusion

  • 18-24kg/m2
  • American Society of Anesthesiologists (ASA) grades I-III
  • The score of Mini Mental state examination≥24

Exclusion

  • Patients with heart, lung and other vital organ disorders
  • The score of Mini Mental state examination≤23
  • Preoperative psychiatric disorders or long-term use of drugs affecting the psychiatric system
  • Have severe visual, hearing, speech impairment or other inability to communicate with the visitor
  • Refuse to sign informed consent

Key Trial Info

Start Date :

April 6 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2022

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT05341375

Start Date

April 6 2021

End Date

April 30 2022

Last Update

May 6 2022

Active Locations (1)

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The First hosptial of Qinhuangdao

Qinhuangdao, China