Status:

COMPLETED

Different Doses of Dexmedetomidine Added to Bupivacaine in Transversus Abdominis Plane Block in Caesarean Delivery

Lead Sponsor:

Mansoura University

Conditions:

Analgesia

Eligibility:

FEMALE

19-40 years

Phase:

NA

Brief Summary

Cesarean birth is a common surgical procedure. After cesarean birth, postsurgical pain may delay recovery, interfere with maternal-newborn bonding, and reduce the breastfeeding if not adequately contr...

Detailed Description

This prospective double-blinded randomized controlled study will be done on parturients that are scheduled for elective cesarean delivery under spinal anesthesia to assess the efficacy of two differen...

Eligibility Criteria

Inclusion

  • Age from 19 to 40 years old
  • American Society of Anesthesiologists (ASA) physical status II patients
  • Singleton pregnancies with a gestational age of at least 37 weeks.
  • Patients undergoing spinal anesthesia for cesarean delivery via a Pfannenstiel incision with exteriorization of the uterus.

Exclusion

  • Age \< 19 or \> 40 years.
  • Height\<150 cm, weight \< 60 kg, body mass index (BMI) ≥40 kg/m2.
  • Inability to comprehend or participate in the pain scoring system.
  • Contraindications to spinal anesthesia (Coagulopathy, increased intracranial pressure, or local skin infection).
  • Hypersensitivity to any drug used in the study.
  • Any hypertensive disorders of pregnancy.
  • Renal impairment or other contraindications to non-steroidal anti-infilamatory drugs (NSAIDS).
  • Significant cardiovascular, renal or hepatic abnormalities.
  • Patients with history of opioid intake, drug abusers or psychiatric patients

Key Trial Info

Start Date :

May 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 14 2023

Estimated Enrollment :

81 Patients enrolled

Trial Details

Trial ID

NCT05342844

Start Date

May 1 2022

End Date

June 14 2023

Last Update

June 23 2023

Active Locations (1)

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Mansoura University-Emergency hospital-ICU

Al Mansurah, Egypt, 35511