Status:
COMPLETED
Association of HY-restricting HLA Class II Alleles, Sex of Firstborn Child, and Pregnancy Outcome in RPL Patients
Lead Sponsor:
Aalborg University Hospital
Conditions:
Recurrent Pregnancy Loss
Eligibility:
FEMALE
18-45 years
Brief Summary
This cross-sectional and prospective cohort study will investigate if sRPL patients with a first born boy who carry ≥1 HY-restricting (HY-r) HLA class II alleles are associated with a lower chance for...
Detailed Description
In a Danish cohort (Kolte et al., 2016, Nielsen et al., 2009) the first pregnancy outcome after admission and the long term live birth rate were associated with carriage of known HY-r HLA class II all...
Eligibility Criteria
Inclusion
- ≥ 3 consecutive pregnancy losses before admission
Exclusion
- Significant uterine malformation
- Chromosomal abnormalities
Key Trial Info
Start Date :
January 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2022
Estimated Enrollment :
583 Patients enrolled
Trial Details
Trial ID
NCT05342948
Start Date
January 1 2016
End Date
October 1 2022
Last Update
March 15 2023
Active Locations (1)
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1
The Centre for Recurrent Pregnancy Loss of Western Denmark, Department of Obstetrics and Gynaecology, Aalborg University Hospital
Aalborg, Denmark, 9000