Status:
COMPLETED
Impact of Anesthesia Maintenance Methods on 5-year Survival After Surgery
Lead Sponsor:
Peking University First Hospital
Conditions:
Aged
Neoplasms
Eligibility:
All Genders
65-90 years
Phase:
NA
Brief Summary
Surgery is one of the major treatment methods for patients with solid organ cancer. And, alone with the ageing process, more and more elderly patients undergo surgery for cancer. Evidence emerges that...
Detailed Description
It is estimated that 234.2 million major surgical procedures are undertaken every year worldwide. Surgery is one of the major treatment methods for patients with solid organ cancer. And, alone with th...
Eligibility Criteria
Inclusion
- Participants will be included if they meet all the following criteria:
- Age ≥ 65 years and \< 90 years;
- Primary malignant tumor;
- Do not receive radiation therapy or chemotherapy before surgery;
- Scheduled to undergo surgery for the treatment of tumors, with an expected duration of 2 hours or more, under general anesthesia;
- Agree to participate, and give signed written informed consent.
Exclusion
- Patients will be excluded if they meet any of the following criteria:
- Preoperative history of schizophrenia, epilepsy, parkinsonism or myasthenia gravis;
- Inability to communicate in the preoperative period (coma, profound dementia, language barrier, or end-stage disease);
- Critical illness (preoperative American Society of Anesthesiologists physical status classification ≥ IV);
- Severe hepatic dysfunction (Child-Pugh class C), or severe renal dysfunction (undergoing dialysis before surgery);
- Neurosurgery.
Key Trial Info
Start Date :
April 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 30 2023
Estimated Enrollment :
1228 Patients enrolled
Trial Details
Trial ID
NCT05343260
Start Date
April 1 2015
End Date
March 30 2023
Last Update
July 31 2025
Active Locations (15)
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1
Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital
Beijing, Beijing Municipality, China, 100034
2
Beijing Shijitan Hospital
Beijing, Beijing Municipality, China
3
Peking University Cancer Hospital
Beijing, Beijing Municipality, China
4
Cancer Hospital of Guangxi Medical University
Nanning, Guangxi, China