Status:

UNKNOWN

Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat

Lead Sponsor:

Rehman Medical Institute - RMI

Conditions:

Sore Throat

Eligibility:

FEMALE

18-60 years

Phase:

PHASE4

Brief Summary

Post-operative sore throat (POST) following General Anesthesia with endotracheal is a common symptom and drains resources. The researchers will compare preoperative gargling of Asprine and Benzydamine...

Detailed Description

Endotracheal intubation commonly causes postoperative sore throat (POST). Its incidence is 22 - 62% in the adult population whereas in children the incidence is 24 to 44%. In adult population peak inc...

Eligibility Criteria

Inclusion

  • Patients of American Society of Anesthesiologists Class 1 and 2 (ASA 1 and 2) scheduled for gynecological surgery under General Anesthesia with Intra tracheal Intubation and expected to finish in less than three hours will be included in the study.
  • Patients of 18- 60 years of age will be included.
  • Patients of Mallampati class 1 and 2 will be selected, as these have easy intubation predicted.
  • Patients qualifying for easy intubation (prediction based on mouth opening, neck mobility etc.) will be selected.
  • Patients in supine position only.

Exclusion

  • Patients who are unable to gargle properly.
  • Patients who require more than 2 attempts at intubation.
  • Patients of Cormack-Lehane Grade 3 and 4 on direct laryngoscopy (multiple intubating attempts may be required).
  • Patients requiring oral cavity instrumentation e.g. N/G tube placement, oral or laryngeal surgeries including tonsillectomies
  • Patients whose head are frequently turned \> 90 degrees with ETT placed in.
  • Patients whose surgery is prolonged beyond 3 hour.
  • Patients who require postoperative mechanical ventilation.

Key Trial Info

Start Date :

April 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05343429

Start Date

April 1 2022

End Date

December 31 2022

Last Update

May 12 2022

Active Locations (1)

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1

Rehman Medical Institute

Peshawar, Khyber Pakhtunkhwa, Pakistan, 25000