Status:
RECRUITING
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
Lead Sponsor:
Mclean Hospital
Collaborating Sponsors:
Beth Israel Deaconess Medical Center
National Institute of Mental Health (NIMH)
Conditions:
Schizophrenia
Schizo Affective Disorder
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia. TMS is a noninvasive way of stimulating the brain, using a ma...
Detailed Description
This study tests the hypothesis that hallucinations in schizophrenia are mediated by network pathophysiology, and that network pathophysiology can be quantified by the functional connectivity of a cer...
Eligibility Criteria
Inclusion
- Diagnosis of schizophrenia or schizoaffective disorder
Exclusion
- substance use disorder in past 3 months
- ambidexterity
- contraindications for TMS or MRI including :
- history of neurological disorder
- history of head trauma resulting in loss of consciousness
- history of seizures or diagnosis of epilepsy or first degree relative family history of epilepsy
- metal in brain or skull
- implanted devices such as a pacemaker, medication pump, nerve stimulator or ventriculoperitoneal shunt
- claustrophobic in MRI
Key Trial Info
Start Date :
October 13 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 31 2026
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT05343598
Start Date
October 13 2021
End Date
October 31 2026
Last Update
March 13 2024
Active Locations (1)
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1
McLean Hospital
Belmont, Massachusetts, United States, 02478