Status:
RECRUITING
Nifedipine Versus Magnesium Sulfate for Late Preterm Tocolysis
Lead Sponsor:
Assiut University
Conditions:
Threatened Preterm Labor
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Objective: This trial is designed to compare between the effectiveness of nifedipine versus magnesium sulfate (MgSO4) for tocolysis in women with threatened preterm labor. Patient Population: The pop...
Eligibility Criteria
Inclusion
- Pregnant women with threatened preterm labor defined as 3 or more uterine contractions in 30 minutes confirmed by cardiotocography.
- Gestational age from 32 week + 0 days to (inclusive) 36 weeks + 0 days.
- Women with singleton or multiple pregnancy.
- Women with preterm prelabor rupture of membranes (PROM) will be included if they have uterine contractions.
Exclusion
- Contraindications for the use of either drugs, such as cardiac disease, hypotension, myasthenia gravis, or renal impairment.
- Contraindications for tocolysis, such as intrauterine demise, intrauterine infection, fetal distress, placental separation, or severe pre-eclampsia.
- Cervical dilatation \> 5 cm.
- Cervical length \> 30 mm by trans-vaginal ultrasound.
- Cervical cerclage.
Key Trial Info
Start Date :
March 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2026
Estimated Enrollment :
264 Patients enrolled
Trial Details
Trial ID
NCT05343806
Start Date
March 1 2023
End Date
February 1 2026
Last Update
December 8 2023
Active Locations (1)
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1
Faculty of Medicine, Assiut University
Asyut, Egypt, 71515