Status:
COMPLETED
Women With Polycystic Ovary Syndrome Are at High Risk for Cardiac Insults
Lead Sponsor:
Tanta University
Conditions:
Cardiac Disease
Eligibility:
FEMALE
30-40 years
Brief Summary
Objectives: Evaluation of the cardiovascular (CV) risk in a sample of CV asymptomatic infertile women with polycystic ovary syndrome (PCOS). Patients \& Methods: 100 infertile PCOS women older than 3...
Detailed Description
Women attending the infertility clinics at Tanta and Benha University Hospitals were eligible for evaluation for PCOS as a cause of infertility. Gynecological evaluation entails data concerning presen...
Eligibility Criteria
Inclusion
- Infertile PCOS women older than 30 years and free of exclusion criteria were enrolled in the study as PCOS group. Fifty non-PCOS women of age- and BMI cross-matched to the enrolled PCOS women with regular menstrual cycles or fertile if married were collected as control (Non-PCOS) group. Only women who signed the written informed consent will be enrolled in the study.
Exclusion
- Age younger than 30 years old, BMI\>35 kg/m2, presence of acute or chronic inflammatory diseases, diabetes mellitus, hyperprolactinemia, thyroid dysfunction, Cushing's syndrome, congenital adrenal hyperplasia, adrenal tumor or ovarian tumor, autoimmune disease, malignancy, central nervous system disease, current or previous use of oral contraceptives within 6 months of enrollment were excluded from the study. Patients had congenital cardiac lesions, manifestations of atherosclerosis or family history of cardiac or cerebrovascular insults, ejection fraction \<50%, regional wall motion abnormalities and significant valvular diseases were excluded.
Key Trial Info
Start Date :
March 21 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 17 2021
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05344547
Start Date
March 21 2020
End Date
November 17 2021
Last Update
April 25 2022
Active Locations (1)
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1
Tanta university
Tanta, El-Gharbyia, Egypt, 13511