Status:

COMPLETED

Evaluation of Safety and Performance of Ialuxid Gel in Treatment of Acne Vulgaris, and Folliculitis

Lead Sponsor:

BMG Pharma

Collaborating Sponsors:

Opera CRO, a TIGERMED Group Company

Conditions:

Acne Vulgaris

Folliculitis

Eligibility:

All Genders

18-45 years

Phase:

NA

Brief Summary

The Research Question of the present study is the following: in a population of men and women affected by acne vulgaris, and folliculitis, will Ialuxid® Gel (hydrogen peroxide, hyaluronic acid and gly...

Detailed Description

Ialuxid® Gel is a non-antibiotic treatment in gel indicated for use in a variety of skin conditions, and also in case of infection. Its principal ingredient is Ialuvance™ Complex, a proprietary associ...

Eligibility Criteria

Inclusion

  • Men or women aged ≥ 18 and ≤ 45 years.
  • Patients diagnosed with acne vulgaris, and folliculitis.
  • a. Only for patients with acne vulgaris: mild to moderate Global Acne Grading Scale score (≤ 30).
  • Patients willing to provide signed informed consent to clinical investigation participation.
  • Patients who agree to discontinue all dermatological treatment and procedures during the study.
  • Patients able to communicate adequately with the Investigator and to comply with the requirements for the study.

Exclusion

  • Pregnant woman, lactating woman, and man or woman of childbearing potential who is planning a pregnancy or is unwilling to use appropriate methods of contraception\* during the study.
  • \*Methods of contraception: hormonal contraceptive, intrauterine device or intrauterine system, double barrier method (condom with spermicide/diaphragm or cervical cap with spermicide), surgical sterilization (vasectomy, tubal ligation, etc.).
  • Patients with history of allergy or hypersensitivity to Hyaluronic Acid or to any other ingredients of Ialuxid® Gel or hypersensitivity skin reaction to Ialuxid® Gel based on skin test results.
  • History of anaphylaxis or severe complicated allergy symptoms.
  • Patients with any dermal systemic pathologies, such as systemic lupus erythematosus, psoriasis, scleroderma.
  • Patients who have used oral drugs for acne vulgaris, and folliculitis in the previous month.
  • Patients who have used topical therapies for acne vulgaris, and folliculitis in the previous month.
  • Use of concomitant treatments or procedures aimed to improve skin condition over the last six months before the enrolment, such as chemical peeling, dermabrasion, laser resurfacing.
  • Patients suffering from infectious diseases that would compromise participation, including herpes simplex virus infection, active hepatitis, or human immunodeficiency virus.
  • Patients at risk in term of precautions, warnings and contra-indications referred in the package insert of Ialuxid® Gel.
  • Patients with any facial aesthetic surgery (such as facial contouring surgery: rhinoplasty, chin, or cheek enhancement (through facial implant) or facial rejuvenation surgery: facelift, eyelid lift, neck lift or facial implants etc.) in the preceding 3 months before the enrolment.
  • Patients who received filler injections of any typology in the face in the preceding 3 months.
  • Patients who received botulinum toxin A injections in the face in the preceding 6 months.
  • Need to have direct or indirect contact with quaternary ammonium salts during the study.
  • Patients unlikely to cooperate.
  • Patients with any other medical condition that, in the opinion of the Investigator, would compromise participation or be likely to lead to hospitalization during the study.
  • Participation in an interventional clinical study or administration of any investigational agents in the previous 30 days.

Key Trial Info

Start Date :

November 11 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 22 2023

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT05345093

Start Date

November 11 2022

End Date

September 22 2023

Last Update

May 21 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

SC Salvosan Ciobanca SRL

Zalău, Sălaj County, Romania, 450117