Status:

COMPLETED

Effect of Computerized Cognitive Training in Persons With MS

Lead Sponsor:

University of Nebraska

Conditions:

Multiple Sclerosis, Relapsing-Remitting

Eligibility:

All Genders

19-60 years

Phase:

NA

Brief Summary

Multiple sclerosis (MS) affects approximately one million people in the United States and 2.5 million worldwide. Between one million and 1.75 million persons with MS (PwMS) worldwide are estimated to ...

Detailed Description

Kathy Healey, MS Specialist and participating personnel on this study, is one of the MS providers at the Nebraska Medicine MS Clinic. She helped determine the following inclusion/exclusion criteria as...

Eligibility Criteria

Inclusion

  • Ages 19-60 inclusive
  • Expanded Disability Status Scale (EDSS) score of 2-5.5 inclusive
  • Relapsing-Remitting MS according to McDonald Criteria
  • 17 or above on the Montreal Cognitive Assessment (MoCA)
  • 70 or above on the Test of Premorbid Functioning (TOPF)
  • 29 or less on the Beck Depression Inventory (BDI-II)
  • Less than 15 on the Generalized Anxiety Disorder (GAD-7)

Exclusion

  • Relapse within the last 6 months
  • Disease modifying treatment (DMT) change within the last 6 months
  • Primary Progressive MS or Secondary Progressive MS according to McDonald Criteria
  • No access to computer/internet
  • Currently undergoing treatment for cognitive impairment
  • Answers a 2 or 3 on the suicidal thoughts question of the BDI-II
  • Answers a 1 on the suicidal thoughts question of the BDI-II and then a Columbia Suicide Severity Rating Scale indicates more than low risk

Key Trial Info

Start Date :

June 28 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 21 2022

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT05345288

Start Date

June 28 2022

End Date

October 21 2022

Last Update

September 29 2023

Active Locations (1)

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1

University of Nebraska Medical Center

Omaha, Nebraska, United States, 68198