Status:

UNKNOWN

Monocyte Soluble Activation Markers sCD14 and sCD163 in Children With Type 1 Diabetes Mellitus

Lead Sponsor:

Assiut University

Conditions:

Type1diabetes

Eligibility:

All Genders

5-18 years

Brief Summary

The study aims to compare serum levels of sCD14 and sCD163 in children with type 1 Diabetes Mellitus with healthy controls, study the distribution of monocyte subsets in children with T1DM , correlate...

Detailed Description

Type 1 diabetes mellitus (T1DM) is T-cell mediated autoimmune disease in which the function of insulin-secreting pancreatic β-cells is impaired due to autoreactive immune cell-mediated destruction (in...

Eligibility Criteria

Inclusion

  • Children of any age and sex diagnosed with T1DM (according to WHO criteria) with a minimum duration of five years will be included.

Exclusion

  • Children with other with coexisting autoimmune, chronic, and acute inflammatory diseases.

Key Trial Info

Start Date :

July 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2023

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT05347836

Start Date

July 1 2022

End Date

August 1 2023

Last Update

April 26 2022

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