Status:

COMPLETED

Observational Study to Evaluate the Influence of Undercast Material Types on Skin Microbiome

Lead Sponsor:

BSN Medical GmbH

Conditions:

Skin Microbiome

Undercast Materials

Eligibility:

All Genders

18+ years

Brief Summary

This clinical study will evaluate the clinical performance and the safety of the CE-marked casting and padding materials when used in routine fracture care without any additional invasive methods and ...

Eligibility Criteria

Inclusion

  • Subject ≥ 18 years of age
  • Patient is physically and mentally able to participate in this study
  • Proper understanding of the Dutch language
  • Signed informed consent
  • Fractures to be treated with a short-arm cast without thumb inclusion for the period of 3 weeks (e.g. 2R3A1 = radial styloid avulsion, 2R3A2 = Simple radial fracture, 2U3A1 = Ulnar fracture of the base of the styloid process, 2U3A2= Simple distal ulna fracture, 2R3B1 = Intraarticular fracture of the styloid process of the radius (not displaced) or Triquetrum fracture (non AO classified))

Exclusion

  • Subject \<18 years of age
  • Pregnancy, breast feeding
  • Participation in other clinical trials
  • Patient is neither physically nor mentally able to participate in this study
  • Non-intact skin in treatment area (including dermatological issues)
  • Patients with impaired (e.g. Cortisone skin, extremely dry skin, parchment skin) or damaged skin with either a surgical wound or a traumatic wound
  • Medical treatment prior casting which could influence the microbiome
  • Known Blood Circulatory Diseases
  • Known Lymphedema or any general disorder of the lymphatic system
  • Known Osteoporosis
  • Known Diabetes
  • Knowing of one of the following illnesses that might require regular systemic medication: cancer, rheumatic disease
  • Intolerability or documented allergies against cast materials
  • Subjects with not "normal" (unusual) hygienic behavior
  • Suspected drug addiction or alcohol abuse
  • Patients diagnosed HIV-positive or with infectious hepatitis based on self-declaration by subjects

Key Trial Info

Start Date :

October 30 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2024

Estimated Enrollment :

108 Patients enrolled

Trial Details

Trial ID

NCT05347927

Start Date

October 30 2022

End Date

December 31 2024

Last Update

January 31 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Ommelander Ziekenhuis

Groningen, Scheemda, Netherlands, 9679 BJ

2

Wilhelmina Ziekenhuis Assen (Assen, NL)

Assen, Netherlands, 9401 RK

3

Leids Universitair Medisch Centrum (Leiden, NL)

Leiden, Netherlands, 2333 ZA