Status:

COMPLETED

Randomized Controlled Trial of Virtual Reality Assisted Guided Imagery (VRAGI) for Pain in Advanced Cancer Patients.

Lead Sponsor:

Prisma Health-Upstate

Collaborating Sponsors:

Clemson University

Conditions:

Cancer Pain

Oncology

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Introduction Patients with advanced cancer often experience high levels of debilitating pain and pain-related psychological distress. Although there is increasing evidence that non-pharmacological str...

Detailed Description

Objectives The primary aim of this pilot study is to measure the improvement in pain using virtual reality assisted guided imagery in participants with advanced cancer. The study will utilize a novel...

Eligibility Criteria

Inclusion

  • \> 18 years of age
  • Advanced cancer, defined as cancer that is incurable including locally advanced and metastatic cancers, with no plan for resection during the study period.
  • Baseline pain score Edmonton Symptom Assessment Scale (ESAS) ≥ 4 (mean score during the screening week).
  • Able to provide consent and willing to comply with all study procedures, as well as comprehend spoken and written English.
  • Have access to a compatible Android, iOS smartphone, personal laptop, or desktop computer (excluding tablets) to complete surveys and respond to emails

Exclusion

  • Have a condition that interferes with VR usage including history of seizure, facial injury precluding safe placement of an HMD, or other visual or hearing impairment that impacts ability to participate.
  • Participated in a previous VR clinical study.
  • Underwent a surgical procedure within 8 weeks.
  • Have a neurocognitive disorder according to past medical history.
  • Have brain metastases.
  • Have a prognosis of \<3 months from the time of enrollment per treating oncologist.
  • Experience current substance abuse.
  • Experienced complex childhood trauma.
  • Diagnosed with serious mental illness.
  • \>65 years of age

Key Trial Info

Start Date :

June 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 28 2025

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT05348174

Start Date

June 1 2023

End Date

February 28 2025

Last Update

March 19 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Clemson University

Clemson, South Carolina, United States, 29634

2

Watermark Counseling

Columbia, South Carolina, United States, 29201

3

Prisma Health

Greenville, South Carolina, United States, 29605