Status:

UNKNOWN

TEOSYAL RHA® 1 for Neck Lines, Perioral Lines and Smiling Lines

Lead Sponsor:

Teoxane SA

Conditions:

Skin Aging

Fine Lines of the Face and Neck

Eligibility:

All Genders

35-70 years

Phase:

NA

Brief Summary

Prospective, low-interventional, multicentric, open-labelled study to assess the performance and safety of skin beautification treatment by TEOSYAL RHA® 1 for fine lines in the neck, perioral region, ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria (General):
  • Healthy adults, 35 to 70 years old seeking an improvement of their aesthetic appearance and beautification of their skin in 3 areas: perioral lines, smiling lines and neck lines.
  • Subjects having given their informed consent.
  • Subjects having wrinkle severity ranked as mild to moderate neck lines (grade 2 or grade 3 on the NLDS)
  • Inclusion Criteria (Cohort) 4. Healthy adult having wrinkle severity in at least one of the two indications (50% for each of the following cohort): i. Moderate to severe perioral rhytids (grade 2 or grade 3 on the PR-SRS) ii. Moderate to severe smiling lines (grade 3 or grade 4 on the SLDS)
  • Exclusion Criteria:
  • Minor subjects
  • Subjects who already had fillers and/or other skin quality treatment(s) in the 6 months preceding the study.
  • Subjects undergoing or planning to undergo peeling treatment or laser/ultrasound-based treatment during the study or having had one of these treatments in the 6 months preceding the study.
  • Subjects showing cutaneous disorders, inflammation or infection (acne, herpes, scars…) at the treatment site or near to this site.
  • Subjects having a known hypersensibility to lidocaine and/or amide local anesthetic agents or hyaluronic acid, or with history of severe allergy or anaphylactic shock.
  • Subjects with autoimmune or cardiac diseases and/or undergoing treatment for heart diseases (beta blockers).
  • Subjects with hepatocellular insufficiency and/or undergoing treatment for liver disease.
  • Subjects suffering from epilepsy or porphyria.
  • Subjects with severe, ongoing and/or uncontrolled disease that may pose a health risk to the subject during the study and/or may have an impact on the study assessments.
  • Subjects receiving or planning to receive high dose Vitamin E, aspirin, anti-inflammatories, or anti-coagulant during the week preceding each injection.
  • Subjects receiving any long-term medical treatment or any treatment that, in the opinion of the clinical investigator, may interfere with test results or put the subject at undue risk.
  • Subjects under guardianship/tutorship.
  • Pregnant women or breastfeeding mother.
  • Subjects participating to another research on human beings or being in an exclusion period for a previous study.

Exclusion

    Key Trial Info

    Start Date :

    October 5 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    May 31 2022

    Estimated Enrollment :

    67 Patients enrolled

    Trial Details

    Trial ID

    NCT05349799

    Start Date

    October 5 2021

    End Date

    May 31 2022

    Last Update

    May 4 2022

    Active Locations (4)

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    Page 1 of 1 (4 locations)

    1

    Site 4

    Alicante, Spain

    2

    Site 3

    Barcelona, Spain

    3

    Site 1

    Bilbao, Spain

    4

    Site 2

    Madrid, Spain

    TEOSYAL RHA® 1 for Neck Lines, Perioral Lines and Smiling Lines | DecenTrialz