Status:

RECRUITING

Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy

Lead Sponsor:

Emory University

Collaborating Sponsors:

Lunair Medical

Conditions:

Obstructive Sleep Apnea

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Obstructive sleep apnea (OSA) is a disorder where a person has recurrent choking episodes during sleep. Surgery can treat OSA and drug induced sleep endoscopy (DISE) is a procedure that surgeons use t...

Detailed Description

Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent choking episodes during sleep. OSA affects over 25 million Americans and is associated with increased risks of hypertensio...

Eligibility Criteria

Inclusion

  • Adult patients (≥ 18 yrs) willing and capable of providing informed consent
  • Obstructive sleep apnea (AHI ≥ 5 events/hour)
  • Must be willing and able to provide informed consent to participate in the study.
  • Interested in surgical treatments of OSA and have consented for a DISE procedure as part of their routine clinical evaluation.
  • Patients are evaluated and cleared by anesthesia prior to the procedure.

Exclusion

  • No significant uncontrolled medical co-morbidities (e.g., uncontrolled hypertension, unstable angina, uncompensated heart failure or COPD).
  • Any medical comorbidity that would prevent the patient from receiving anesthesia or having surgery
  • Inability to tolerate negative pressure ventilator or perform PFT (i.e. claustrophobia)
  • No incapacitating disability that interferes with execution of the protocol

Key Trial Info

Start Date :

June 30 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT05350332

Start Date

June 30 2022

End Date

June 1 2026

Last Update

October 20 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Emory University Hospital Midtown

Atlanta, Georgia, United States, 30308