Status:
ACTIVE_NOT_RECRUITING
Motor Learning After Cerebellar Damage: The Role of the Primary Motor Cortex
Lead Sponsor:
Albert Einstein Healthcare Network
Collaborating Sponsors:
Medical University of South Carolina
Conditions:
Cerebellar Ataxia
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
This study will determine (1) whether baseline inhibitory activity in the primary motor cortex can predict motor learning ability in individuals with cerebellar degeneration, and (2) whether modulatin...
Detailed Description
Cerebellar damage causes the disabling movement disorder ataxia, which is characterized by impaired movement coordination affecting all body movements. In the arms, ataxia causes reaching movements wi...
Eligibility Criteria
Inclusion
- Diagnosis of cerebellar ataxia from cerebellar degeneration
- Normal or corrected-to-normal vision
- Normal or corrected-to-normal hearing
- Meet safety criteria for receipt of transcranial magnetic stimulation
Exclusion
- Extrapyramidal signs on neurologic examination
- History of alcohol or illicit drug abuse
- Peripheral sensory loss in the arms
- Cognitive or attention deficits that interfere with testing, the capacity to understand and follow task instructions, or the capacity to provide informed consent
- Orthopedic injury or pain in the arms
Key Trial Info
Start Date :
July 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 19 2026
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT05351255
Start Date
July 1 2022
End Date
December 19 2026
Last Update
September 15 2025
Active Locations (1)
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1
Moss Rehabilitation Research Institute
Elkins Park, Pennsylvania, United States, 19027