Status:
COMPLETED
Impact of a Newly Formulated Toothpaste in Tooth Staining Associated With Chlorhexidine Rinses
Lead Sponsor:
Universidad Complutense de Madrid
Collaborating Sponsors:
Dentaid SL
Conditions:
Tooth Staining
Periodontitis
Eligibility:
All Genders
30-69 years
Phase:
NA
Brief Summary
Dental staining may interfere with compliance with chlorhexidine mouth rinse use Thus, developing strategies to control tooth staining associated with chlorhexidine use may be relevant for improving ...
Detailed Description
The primary objective of these RCTs will be to evaluate the capacity of preventing tooth staining, associated with the use of a chlorhexidine mouth rinse, adjunctive to subgingival instrumentation (st...
Eligibility Criteria
Inclusion
- 30-69 years old.
- Periodontitis patients, in stages I-III, requiring steps 1 and 2 of periodontal treatment including full-mouth subgingival instrumentation.
- Systemically healthy, following the criteria of the American Society of Anesthesiologists (ASA), for patients ASA type I or II (see also exclusion criteria).
- Presence of at least three evaluable teeth in each quadrant.
- No orthodontic banding or removable prosthesis.
- Subjects willing to participate and comply with the requirements of the study.
Exclusion
- Acute periodontal conditions.
- Antibiotic intake within the previous month.
- Chronic use of analgesic or anti-inflammatory drugs.
- Pregnant women.
- Any adverse medical history (diabetes, osteoporosis, immunosuppression…) or long-term medication (chemotherapy and immunosuppression treatment; pharmacological treatment associated with gingival overgrowth such as the use of phenytoin, phenobarbital, lamotrigine, vigabatrin, ethosuximide, topiramate, primidone, nifedipine, amlodipine, verapamil, cyclosporine) influencing gingival conditions.
- Conditions which require antibiotic prophylaxis (infectious endocarditis, cardiac valve prosthesis…).
Key Trial Info
Start Date :
October 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2024
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT05354986
Start Date
October 1 2022
End Date
January 31 2024
Last Update
May 9 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Faculty of Dentistry, University Complutense of Madrid (UCM)
Madrid, Spain, 28040