Status:
UNKNOWN
A Novel Functional Imaging Technique With FLT-PET/MRI For Staging, Response Assessment and Radiation Treatment Planning in Cervix Cancer
Lead Sponsor:
National Cancer Centre, Singapore
Conditions:
Image, Body
Cervix Cancer
Eligibility:
All Genders
21-99 years
Phase:
NA
Brief Summary
This pilot study aims to monitor early tumour response based on \[18F\]FLT-PET/MRI scans and to determine the feasibility of personalised radiotherapy to spare active bone marrow areas identified by \...
Eligibility Criteria
Inclusion
- Have given written informed consent, with the understanding that consent may be withdrawn at any time without prejudice
- Histologically or cytologically confirmed cervical carcinoma
- FIGO staged IB to IVA
- Underwent MRI pelvis
- Underwent FDG-PET/CT or MRI abdomen or CT thorax and abdomen or Chest X ray for routine staging
- Planned for radical radiotherapy with or without chemotherapy
- No distant metastasis in staging work up
- ECOG 0-2
- Age 21 or over (no upper age limit)
Exclusion
- Patients scheduled for neoadjuvant chemotherapy
- Patients with previous hysterectomy or radiotherapy to the pelvis
- Patients who are pregnant or lactating
- Patients who do not meet the above mentioned inclusion criteria
- Patients who refuse to give and/or sign the informed consent
- Patients who currently have a pacemaker
- Patients who have a history of serious adverse events related to a previous MRI or PET/CT
- Patients who are unable to undergo MRI scanning
- Patients with a known allergy against any component of the contrast enhancing agent
- Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow up schedule; these conditions should be discussed with the patient before registration in the trial.
Key Trial Info
Start Date :
May 14 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2022
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT05355558
Start Date
May 14 2019
End Date
December 31 2022
Last Update
May 2 2022
Active Locations (1)
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1
National Cancer Centre Singapore
Singapore, Singapore, 169610